Nucleosides and Analogues
Medchemexpress LLC 2-amino-2'-deoxyadenosine | 4546-70-7 | MFCD00047240 | 99.6% | 266.26 g/mol | C10H14N6O3 | 1 ML
2-Amino-2'-deoxyadenosine is a deoxyribonucleoside analog used as a building block in oligonucleotide synthesis and nucleoside research. It is supplied as a ready-to-use solution in DMSO or as a solid, and is characterized by high purity for laboratory applications.
- Suitable for oligonucleotide synthesis and nucleoside modification studies.
- Available as a 10 mM solution in DMSO and in solid pack sizes for scale-up.
- High purity (99.62%) for research-grade applications.
- Molecular weight 266.26 g/mol; chemical formula C10H14N6O3.
Medchemexpress LLC 2'-Deoxyadenosine 5'-triphosphate disodium | 74299-50-6 | 99.9% | 535.15 | 10 MG
2'-Deoxyadenosine 5'-triphosphate disodium is a nucleotide with important biological activities. It serves as a substrate for a variety of polymerases, including DNA polymerases and reverse transcriptases. This compound plays a key role in DNA synthesis and reverse transcription. It is also widely used in in vitro reactions in molecular biology research.
- Serves as a substrate for a variety of polymerases
- Plays a key role in DNA synthesis
- Plays a key role in reverse transcription
- Widely used in in vitro reactions in molecular biology research
Medchemexpress LLC 2'-Deoxyadenosine monohydrate | 16373-93-6 | 99.89% | 269.26 | 5 G
2'-Deoxyadenosine monohydrate is an adenine nucleoside with multiple biological roles, including inhibiting glucose-stimulated insulin release and islet cyclic AMP (cAMP) accumulation. It activates caspase-3 and promotes apoptosis, and inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity. It has shown an anticancer effect on colon cancer and appears as a white to off-white solid.
- Inhibits glucose-stimulated insulin release
- Inhibits glucose-stimulated increases in islet cyclic AMP (cAMP) accumulation
- Activates caspase-3
- Promotes apoptosis
- Inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity
- Demonstrated inhibitory effect on the growth of various cells, including anticancer effect on colon cancer
- Appears as a white to off-white solid
Medchemexpress LLC N6-Isopentenyladenosine | 7724-76-7 | 99.4% | 335.36 | 1 ML
N6-Isopentenyladenosine (Riboprine) is an RNA modification found in cytokinins, which are known to regulate plant growth and differentiation. It is also present in a subset of tRNAs, where it enhances the efficiency and accuracy of translation. This compound is an end product of the mevalonate pathway and functions as an autophagy inhibitor, demonstrating interesting anti-melanoma activity.
- RNA modification found in cytokinins
- Regulates plant growth/differentiation
- Improves efficiency and accuracy of translation in tRNAs
- End product of the mevalonate pathway
- Autophagy inhibitor
- Exhibits anti-melanoma activity
Medchemexpress LLC 7-deaza-2'-deoxyadenosine | 60129-59-1 | >=97.0% | 250.25 g/mol | C11H14N4O3 | 50 MG
7-deaza-2'-deoxyadenosine is a deoxynucleoside analog used in biochemical research and nucleotide chemistry as a building block for oligonucleotide synthesis and related assays. It is typically supplied as a white solid for laboratory research and is intended for research use only.
- deoxynucleoside analog for nucleotide chemistry
- used as a building block in oligonucleotide synthesis
- supplied as a solid in milligram quantities for laboratory research
- intended for research use only, not for human or clinical use
Medchemexpress LLC 2'-Deoxyguanosine | 961-07-9 | 267.25 | 1 G
2'-Deoxyguanosine is a purine nucleoside with a variety of biological activities. It can induce DNA division in mouse thymus cells and is a potent cell division inhibitor in plant cells. In vitro, it inhibits the clonal growth of HL-60 and K562 leukemia cells with IC50 values of 50 and 80 μM, respectively.
- Classified as an endogenous metabolite related to cancer
- Analytical standard intended for research and analytical applications (for standard version HY-17563R)
Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 10 MM * 1 ML
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase.
- Nucleoside analogue
- Can be incorporated into de novo-synthesized telomeres by telomerase
- Rapid cell death for the vast majority of cancer cell lines tested with IC50s of between 0.7-2.9 μM (in vitro)
- Causes a decrease of the tumor growth rate in A549 lung cancer cell-based mouse xenograft studies, superior to that observed with 6-thioguanine treatment (in vivo)
- Increases telomere dysfunction in tumor cells in vivo
- Appearance: Solid
- Color: White to yellow
Medchemexpress LLC Deoxyguanosine triphosphate trisodium solution | 93919-41-6 | 99.95% | 573.13 | 57.31 MG
Deoxyguanosine triphosphate (dGTP) trisodium solution (100mM) is a nucleotide precursor in cells for DNA synthesis. It is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.
- Nucleotide precursor for DNA synthesis.
- Used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.
- High purity: 99.95%.
Medchemexpress LLC 2'-Deoxyguanosine | 961-07-9 | >99.9% | 267.25 | 5 G
2'-Deoxyguanosine is a purine nucleoside with diverse biological activities. It can induce DNA division in mouse thymus cells and acts as a potent cell division inhibitor in plant cells. It inhibits the clonal growth of HL-60 and K562 leukemia cells with IC50 values of 50 and 80 μM, respectively. This product is intended for research use only.
- Induces DNA division in mouse thymus cells.
- Acts as a potent cell division inhibitor in plant cells.
- Inhibits clonal growth of HL-60 and K562 leukemia cells.
- Intended for research applications.
Medchemexpress LLC 3′-Deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 5 MG
3′-Deoxyguanosine is a derivative of Guanosine. It interacts with human purine nucleoside phosphorylase through hydrogen bonding with residues like Glu201 and Asn243. This compound shows moderate displacement activity for [3H]-guanosine in rat meninges and is useful for studying the mechanism of guanosine receptors and purine metabolism.
- Derivative of Guanosine.
- Interacts with human purine nucleoside phosphorylase via hydrogen bonding.
- Exhibits moderate displacement activity for [3H]-guanosine in rat meninges.
- Useful for studying guanosine receptor mechanisms and purine metabolism.
- For research use only.
Medchemexpress LLC 2'-Deoxyguanosine | 961-07-9 | 100.0% | 267.25 | 25 MG
2'-Deoxyguanosine is a purine nucleoside with various biological activities. It can induce DNA division in mouse thymus cells and acts as a potent cell division inhibitor in plant cells. It also demonstrates antiproliferative and antiviral effects against several cell lines and viruses.
- Induces DNA division in mouse thymus cells.
- Acts as a potent cell division inhibitor in plant cells.
- Inhibits clonal growth of HL-60 and K562 leukemia cells.
- Exhibits antiviral activity against varicella zoster virus (VZV) Oka strain.
- Exhibits antiviral activity against human cytomegalovirus (HCMV) AD 169 strain.
- Exhibits antiviral activity against herpes simplex virus-1 VR-3 strain.
- Exhibits antiviral activity against herpes simplex virus-2 (HSV-2) Ms strain.
Medchemexpress LLC 2'-Deoxyadenosine monohydrate | 16373-93-6 | 99.9% | 269.26 | 10 G
2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release and glucose-stimulated increases in islet cyclic AMP (cAMP) accumulation. It activates caspase-3 and promotes apoptosis, and inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). This compound can inhibit the growth of various cells and has an anticancer effect on colon cancer.
- Inhibits glucose-stimulated insulin release
- Activates caspase-3 and promotes apoptosis
- Inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity
- Inhibits the growth of various cells
- Demonstrates an anticancer effect on colon cancer
- For research use only
Medchemexpress LLC 2'-Deoxyadenosine monohydrate | 16373-93-6 | MFCD00149364 | >99.8% | 269.26 | 100 G
2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. It also inhibits glucose-stimulated increases in islet cyclic AMP (cAMP) accumulation, activates caspase-3, and promotes apoptosis. Additionally, it inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH) and the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer. It is for research use only and not sold to patients.
- Inhibits glucose-stimulated insulin release.
- Inhibits glucose-stimulated increases in islet cyclic AMP (cAMP) accumulation.
- Activates caspase-3.
- Promotes apoptosis.
- Inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH).
- Inhibits the growth of various cells.
- Has an anticancer effect on colon cancer.
Medchemexpress LLC Adenosine, 2-amino-2'-deoxy- | 4546-70-7 | MFCD00047240 | 99.6% | 266.26 g·mol⁻¹ | C10H14N6O3 | 5 G
2-Amino-2'-deoxyadenosine is a modified deoxyribonucleoside (CAS 4546-70-7) used as a building block in oligonucleotide synthesis and nucleic acid research. Supplied for research use only, it is offered in solid and solution formats and accompanied by analytical documentation to support quality and reproducibility.
- High purity (99.6%).
- Available in multiple sizes, including 5 g and solution formats.
- Molecular weight 266.26 g·mol⁻¹; formula C10H14N6O3.
- Certificate of analysis available for batch verification.
- Intended for research use only; not for human or veterinary use.
Cambridge Isotope Laboratories 8-Hydroxy-2-deoxyguanosine (unlabeled) 25 ug/mL in water 1 2 mL
8-Hydroxy-2-deoxyguanosine (unlabeled) 25 ug/mL in water 1 2 mL
